Lymphocyte subpopulations in thymus and blood from patients with myasthenia gravis.
نویسندگان
چکیده
منابع مشابه
Thymectomy in Patients with Myasthenia Gravis
A case of myasthenia gravis in a 15 years old girl is pre·sented. The disease was present for 5 years before thymectomy was performed. Indications for thymectomy, preoperative preparation, anesthetic and surgical management is -discussed.
متن کاملLymphocyte subpopulations and surface membrane immunoglobulins in myasthenia gravis.
Lymphocyte subpopulations were studied in 16 myasthenic patients by means of E and EA7s rosettes and surface membrane immunofluorescence. Myasthenic patients showed an increase in lymphocytes with surface IgM an IgD when compared to a control group. In female patients this increase was highly significant, and lymphocytes bearing membrane IgG and IgA were also augmented. No difference was found ...
متن کاملLymphocyte function in myasthenia gravis.
Mitogen-induced blastoid transformation of peripheral blood lymphocytes from patients with myasthenia gravis was studied using a microplate culture technique and evaluated with 3H-thymidine incorporation. It was found that both phytohaemagglutinin and pokeweed mitogen responses decreased significantly in patients with myasthenia gravis. In myasthenic crisis, indices of stimulation by phytohaema...
متن کاملAssociation between myasthenia gravis and HLA antigens in patients
Introduction: Myasthenia gravis is a disease of neuromuscular junction. Familial cases have been reported. Relation between myasthenia gravis and HLA antigens has been seen in many studies from different parts of the world. The aim of this study is determination of association between HLA class I haplotypes and myasthenia gravis in Kerman province. Methods: In this cross sectional study 44 my...
متن کاملAssociation of HLA-DQA1*0101/2 and DQB1*0502 with Myasthenia Gravis in Southern Iranian Patients
Background: Myasthenia gravis is an autoimmune disorder of neuromuscular junction characterized by skeletal muscle weakness and fatigability. Different genes may control the induction and clinical presentation of this disease. Various HLA alleles are reported as predisposing or protective genetic elements in myasthenia gravis. Objective: The aim of this study was to investigate the probable as...
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ژورنال
عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry
سال: 1979
ISSN: 0022-3050
DOI: 10.1136/jnnp.42.1.29